{"id":177878,"date":"2022-12-13T13:30:58","date_gmt":"2022-12-13T06:30:58","guid":{"rendered":"https:\/\/unair.ac.id\/sensorineural-hearing-loss-in-juvenile-cml\/"},"modified":"2022-12-14T16:29:59","modified_gmt":"2022-12-14T09:29:59","slug":"sensorineural-hearing-loss-in-juvenile-cml","status":"publish","type":"post","link":"https:\/\/unair.ac.id\/en\/sensorineural-hearing-loss-in-juvenile-cml\/","title":{"rendered":"Sensorineural Hearing Loss in Juvenile CML"},"content":{"rendered":"\n<p>Chronic myeloid leukemia (CML) is a type of myeloproliferative neoplasm (MPN) in which granulocytes are the primary proliferating cells. CML in pediatric patients (juvenile CML) is an uncommon MPN, representing 2\u20133% of children newly diagnosed with leukemia. Sensorineural hearing loss that progresses rapidly is an uncommon early sign of a hematological disorder in patients with CML. This article presents the case of a 10-year-old patient with complaints of bilateral hearing loss for 2 weeks. <\/p>\n\n<p>Pure-tone audiometry indicated sensorineural hearing loss of the left ear and mixed hearing loss of the right ear. After an in-depth evaluation of a bone marrow smear and positivity for the BCR-ABL fusion gene, it was concluded that the patient had chronic-phase juvenile CML. However, hearing loss recovery after hydroxyurea therapy could not be observed because the patient died after suffering an uncontrolled seizure on day 14 of hospitalization. <\/p>\n\n<p>Author : dr. Paulus Budiono Notopuro, dr. Sp.PK(K) \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Full paper can be accessed here:\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9288187\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9288187<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chronic myeloid leukemia (CML) is a type of myeloproliferative neoplasm (MPN) in which granulocytes are the primary proliferating cells. CML in pediatric patients (juvenile CML) is an uncommon MPN, representing 2\u20133% of children newly diagnosed with leukemia. Sensorineural hearing loss that progresses rapidly is an uncommon early sign of a hematological disorder in patients with [&hellip;]<\/p>\n","protected":false},"author":79,"featured_media":177154,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[49],"tags":[9001,14038],"class_list":["post-177878","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-article","tag-aip-en-2","tag-aip-dosen-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Sensorineural Hearing Loss in Juvenile CML - 51动漫 Official Website<\/title>\n<meta name=\"description\" content=\"Pure-tone audiometry indicated sensorineural hearing loss of the left ear and mixed hearing loss of the right ear.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unair.ac.id\/en\/sensorineural-hearing-loss-in-juvenile-cml\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sensorineural Hearing Loss in Juvenile CML - 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