UNAIR NEWS – Patients with kidney failure in Indonesia keep growing in number.Most of them are from complications of hypertension anddiabetes mellitus(DM).According to data from the Indonesian Nephrology Association (PERNEFRI), there are currently about 300,000 people with renal failure in Indonesia, and the number increases 10% annually.
Kidney failure happens as kidneys can not function normally to clean up the waste of metabolism in the body, such as creatinine, toxic substances that exist in the blood of patients with kidney failure, so it needs filtering.
In the last decade,hemodialysis(HD) is a kidney therapy rapidly developed in many countries.It increases the life expectancy of the patients.Hemodialysisrequires a dialysis machine and a special filter called adializer(asemipermeablemembrane) to cleanse the blood, where the blood is removed from the patient’s body and fed into an out-of-body machine.
Semipermeabelmembranecommonly used ishollow fibermembrane,which is a commercial membrane used and unfortunately has less optimal performance, so many patients with kidney failure experience fatality (died).
This fact then encouragedFaculty of Science and Technology (FST) of 51动漫 to seek innovations potential to improve the performance ofhemodialysismembranesused today.The four students are Bella Prelina (team leader), Januardi Wardana, Ahya Isyatir Rodliyah, and Zakiyatus Syukriyah.
Their research then written as a proposalfor Creativity ProgramExacta Research (PKM-PE) titled “Innovation of Hollow FiberPolietersulfon (PES) Membrane with Zeolite Modification for Creatinine Hemodialysis”.This proposal passed the selection and granted them the research grants from the Kemenristekdikti in 2017 PKM program.
According to Bella Prelina, this study provides a renewable innovation in the manufacture ofhollow fibermembranes.The basic material used is the form of composite materials, polietersulfonmodified withzeolite.Both materials have good qualities forhemodialysis membranesbecause of their non-toxic properties.In addition,zeolitesalso have the ability as anadsorbent, so it is expected to give better performance, said Bella.
This study was conducted51动漫 and AMTEC Malaysia.The process started with zeolite production using thehydrothermalmethodat 100掳C. The next process was to makedopesolutionadded withzeolite,then printed with a membrane-printing device.
“The dopesolutionis apolyethersulfone dissolved indimethyl formamide.The membrane printing uses inversion method, which is changing the polymer phase from solution (dope) into solid membrane, “added Januardi and Zakiyatus.
Then the membrane printed then received a post treatmentto maintain the quality of the membrane.Then there is the filtration test.The membrane has high flux and rejection value.In addition,zeolitemodificationcan also alter the chemical characteristics ofpolyethersulfoneso it improves the membrane performance.
“Thehollow fibermembraneformed then tested for filtration using creatinine solution.The filtration process was performed for 15 minutes, then its flux and creatinine rejection capability was measured, and test results showed that the average time produced was faster than the commercial membranes, and the membrane was able to withstand creatinine at 91.92%, a considerable number , ” said Bella.
Thus it is clear that the administration ofzeoliteas a modification of the membrane can affect the speed of filtration and rejection forcreatininehemodialysis, thus it has the potential forcreatininehemodialysis.(*)
Editor: Bambang Bes.
