UNAIR NEWS – Indonesia as an archipelagic country is surrounded by vast waters, almost 70%. It is known to have a great biodiversity because there are various types of animals, plants and coral reefs that grow in the territorial waters of Indonesia.This great natural wealth has inspiredProgram team in thefield of Exacta Research (PKM-PE) from theand Technology (FST) of 51动漫 to conduct research onsponge.
Isolate namedSponge-6.1is expected to become one of the drug candidates useful for the health of Indonesia.Sponge-6.1isolatescontain various types of active substances, such asflavonoidsand other compounds are suspected to inhibit the growth of pathogenic bacteria such asStreptococcus pneumoniae.
According to Dina Lutfiana, leader of the PKMPE Team, theSponge-6.1isolate isbelieved to be a drug candidate to inhibit the growth ofStreptococcus pneumonia, the bacteriacausingpneumonia听.
“We hypothesized that this isolate can inhibitStreptococcus pneumoniae, because during the Field Work Practice (PKL), I investigated that theSponge-6.1isolatescan inhibit the growth ofStreptococcus sp., Staphilococcus sp.,and several other bacteria.It was from this point our team submitted a proposal and managed to qualify for funding from Kemenristekdikti, and the research could continue, “he said.
Besides Dina Lutfiana, this team also includes Jefpry Supryanto Sianturi, William Khodry, Denika Liyan Nor Wibowo, and Dwi Yulian Fahruddin.
They conducted research in collaboration with LIPI, and they conducted the research for two weeks at the Laboratory LIPI Bandung.The initial stage is done by isolating thesponge, which was coincidentally existing in the lab of LIPI. After isolatingSponge-6.1, the study continued by testing the activity of the bacteriaStreptococcus pneumoniaetreated with isolates.The results showed that isolates can inhibit the growth ofStreptococcus pneumoniaebacteriawith administration at a certain concentration.
As the head of the PKM team, Dina hopes that theSponge-6.1isolatecan be used as one of the future drug candidates to be able to produce health benefits.
“So far, our research has reached the stage of testing the content of secondary metabolites of isolatesSponge-6.1,” said Dina. If the content of secondary metabolites existing in these isolates can be identified, it is possible to synthesize a compound similar to drugs usedfor pneumonia and the balance of aquatic ecosystems can be preserved.(*)
Editor: Bambang Bes
