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UNAIR expert reviews role of probiotics in improving intestinal immune system

Dr. Alpha Fardah Athiyyah, dr., Sp.A (K)., one of the experts at Airlangga University. (Illustration: Nuri Hermawan)

UNAIR NEWS –Probiotics are live bacteria that can benefit human health when given the right dose, especially in improving the innate immune system in the intestines.听It is the opening statement of Dr.听Alpha Fardah Athiyyah, dr., Sp.A (K)., in her scientific paper pulished on UNAIR NEWSon Monday, February 1.

In the article about the role of probiotics, dr.听Alpha, one of the experts 51动漫 (UNAIR) explained that the immune system of the intestinal mucosa surface exposed to the outside world has an important role in the immune system to fight infection.听So disorders that occur in the intestinal mucosal immune system certainly play a role in the occurrence of disease.

In a journal article a entitled, dr.听Alpha also explained that there are several known working mechanisms of probiotics, such as increasing the ratio of good bacteria likeBifidobacteria听补苍诲 尝补肠迟辞产补肠颈濒濒颈听compared to disease-causing bacteria and compete with disease-causing bacteria for nutrition and adhesions on the surface of the intestines.

“Furthermore, probiotics also work to increase the production of mucin or mucus layer for the body’s defense, increase anti-microbial activity, and influence the intestinal immune response,” she explained.

She also explained that her research used a combined probiotics with a dose of 1 脳 109CFU consisting ofLactobacillus acidophilus听,听听L. casei subsp.听Casei听,听听L. rhamnosus听,听听L. bulgaricus听,听听Bifdobacterium breve听,听听B. infantis, andStreptococcus thermophilus.听Lipopolysaccharide(LPS), she continued, is made ofEscherichia coliso it can resemble bacterial exposure.听

“Our results show that probiotics can enhance the immune system’s response to disease-causing bacteria.听This result is in line with research conducted in Argentina and Japan, although this study only uses one type of probiotic, Lactobacillus casei, ” she explained.

At the end, she also emphasized that many studies show different results with this study. Therefore, she argued, the differences were based on research objectives and uncertain mechanisms in understanding the innate immune response.

“However, from studies on the probiotics and non-probiotics when exposed to this LPS, we can conclude that combination probiotics can increase the innate intestinal immune response and maintain a balance of intestinal mucosal immune response against disease-causing bacteria,” she concluded.

: Nuri Hermawan

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